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Veteran Study Reveals Dementia Risk with Even Mild Traumatic Brain Injury

A research conducted in Memphis Veterans Affairs Medical Center found that history of even a mild traumatic injury may lead to the risk of Dementia.

Researchers at Memphis Veterans Affairs Medical Center analyzed data from thousands of US veterans. After the study, they came to the conclusion that people with the history of mild traumatic brain injury, including minor brain injuries without loss of consciousness, have twice the risk of developing dementia if compared with the people with no history of brain injuries.

The study was conducted by Jack Tsao and a team from Memphis Veterans Affairs Medical Center. It included the data of 358,000 veterans. Almost all veterans involved in the study were male participants. Half of the participants were diagnosed with brain injuries. Other half participants involved were with no such history.

The study found that the veterans with mild traumatic brain injury without loss of consciousness had 2.4 times more chances of developing dementia than the veterans without brain injury. The chances of veterans who lost their consciousness were likely to be diagnosed with dementia 2.5 times higher. Veterans with moderate-to-severe brain injuries were supposed to have 3.77 times higher risk.

The study also revealed that diagnosis of dementia tends to occur about 1.5 Years earlier in the people with brain injuries than the people with no such history.

The research was published in the JAMA Neurology on May 7, 2018. Researchers proclaimed that they have observed the dose-response association between TBI severity and the diagnosis of dementia. Further, the study revealed that even mild TBI with no loss of consciousness was associated with more than 2-fold increase in the risk of dementia diagnosis after adjusting for demographic factors and medical & psychiatric comorbidities.

Recently, a study on cerebral microbleeds (CMBs) was published in JAMA Neurology. It reported that the cerebral microbleeds are not involved in predicting 3-month death or disability in intracerebral hemorrhage. This study involved participants with CMBs (n=120) and no CMBs (n=47). A total of 167 individuals participated in the study.